Enhanced TDS
Identification & Functionality
- INCI Name
- Manufactured By
- Cosmetic Ingredients Functions
- Technologies
- Product Families
Features & Benefits
Applications & Uses
- Markets
- Applications
- Application Format
- Hair Care Applications
- Skin Care Applications
- Sun Care Applications
- Use Level
- 0.8 - 5 % masks, 0.8 - 5 % night cream, 0.8 - 5 % day cream
- Efficacy
- scavenger of oxygen radicals and hydroxyl radicals
- mimics superoxide-dismutase activity
- stimulation of oxygen consumption/cell activity
- increases the biosynthesis of dermal collagen
- reduction of fine lines and wrinkles
- increase of skin density, thickness and re-epithe- lialization
- skin remodeling: effective for example against scars and stretch marks
The idea behind the development of Omega-CH-Activator® was to have a non animal derived collagen:
- To have present the same amino acids with their efficacy
- To have them in the same concentration like in collagen
- But to have no animal derived product.Obviously this new product has a different spectrum of effect, which is shown in table 1.
Efficacy Collagen Omega-CH-Activator® Reference Moisturizer ++ + StimulationMetabolicActivity - ++ 1 Buffer Capacity + ++ Stimulation growth of Kera- tincytes - + 2,3 Stimulation of Collagen- synthesis of Fibroblasts - ++ 4,5 Radical Sca- venger/Quencher - ++ 6,7 Superoxide-Dismutase Action - ++ 8,9 Penetration - ++ Denaturation at 30 - 37°C ++ - Table 1 Comparison of the Efficacy of Collagen and Omega-CH-Activator®
We measured the scavenging efficacy of OmegaCH-Activator® in vitro, by prevention of degradation of Hyaluronic acid in solution. The enzyme system Xanthin/Xanthinoxidase is producing very quickly OH-Radicals. When added to Hyaluronic acid solution, the viscosity of the solution is decreasing due to the degradation of the polymer by the radicals. As you can see in figure 2, the degradation was inhibited by 55 % with an addition of 0,8 % of Omega-CH-Activator®.. Product X tested is a common commercially available antioxidant.
Figure 2 Enzyme: Xanthinoxidase / Xanthin HA: Hyaluronic Acid
- HA without enzyme
- HA with enzyme
- HA with enzyme + 0.8 % Omega-CH-Activator®
- HA with enzyme + 0.8 % product X
The data show that with a concentration of only 0,8 % of Omega-CH-Activator® a good protection of the skin against environmental impact is possible.
The copper tripeptide GHK-Cu is another important component of Omega-CHS-Activator. In a randomized, double blind, placebo-controlled study of 67 volunteers, GHK-Cu and a placebo were applied twice daily for 12 weeks on facial skin. GHK-Cu improved skin laxity, clarity and appearance; reduced f ine lines, coarse wrinkles and mottled hyperpigmentation; and increased skin density and thickness. Numerous other studies are available in literature for GHK-Cu. Loren Pickart has suggested the following influence of GHK-Cu on skin renewal cycle.
Omega-CH-Activator® is an ideal Anti-Ageing active ingredient, protecting the skin during the day against environmental impact and regenerating the skin due to multifunctional efficacy in the night.- Application Information
Omega-CH-Activator® is suitable for use in high qua- lity cosmetic products like facial creams, facial masks, ampoules, body lotions, after-sun lotions, and after shave products.
Properties
- Physical Form
- Soluble In
- Appearance
- Clear, slight yellow solution
- SDS Physical and Chemical Properties
Value Units Test Method / Conditions Insoluble in Lipophilic substances - - Soluble In Water - - Oxidising Properties None - - Explosive Properties None - - Auto Flammability None - - Density 1.08 - 1.15 g/ml - pH Value 6 - 7 - - Odor Typical smell - - Appearance Clear, slight yellow solution - - - Composition
Value Units Test Method / Conditions Rokonsal MEP 0.22 % - Nipaginester 0.1 % - - Characteristics
Value Units Test Method / Conditions Amino Acids Content 4.8 % - Nitrogen Content 2.1 - 2.4 % - pH Value 6.0 - 7.0 - - Density (at 20°C) 1.08 - 1.15 g/cc - Water Content 48 - 55 % -
Regulatory & Compliance
- Certifications & Compliance
Safety & Health
- Toxicology
Omega-CH-Activator® has been tested adequately with regard to its toxicology, please see separately available report. Mutagenicity (Ames-Test): Omega-CH-Activator® shows no negative results in the Salmonella Typhimurium Reverse Mutation Assay. Photo-allergic and photo-toxic effects: UVA exposed photo patch test with the product shows no photo-allergic or photo-toxic effects.
Storage & Handling
- Shelf Life
- min. 24 months
- Storage and Shelf Life Information
Omega-CH-Activator® should be stored in dark at 10°C - 20°C. Shelf life is at least two years in closed original containers.